Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1990-1-3
pubmed:abstractText
The effect of selenium supplementation was evaluated in 81 patients with acute myocardial infarction in a double-blind, placebo-controlled study. Patients were randomised into two treatment groups receiving either selenium-rich yeast (100 micrograms/day) or placebo in addition to conventional drug therapy for a 6-month period. During treatment the mean serum selenium concentration increased from 82 micrograms/l to 122 micrograms/l (p less than 0.001) in the selenium supplemented group and remained unaltered in the placebo group (83 micrograms/l). During the 6-month follow-up period there were 4 cardiac deaths in the placebo group whereas no patients in the selenium group died during the follow-up period. Furthermore, there were 2 nonfatal reinfarctions in the placebo group and one nonfatal reinfarction in the selenium group. The results encourage further studies to evaluate the efficacy of antioxidants in the prevention and therapy of acute myocardial infarction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0034-5164
pubmed:author
pubmed:issnType
Print
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
249-52
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Effect of selenium supplementation after acute myocardial infarction.
pubmed:affiliation
Department of Public Health Science, University of Oulu, Finland.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial