Linked Life Data

2685516

Source:http://linkedlifedata.com/resource/pubmed/id/2685516

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1989-12-27
pubmed:abstractText
The invasion of Candida albicans strains into the chorio-allantoic membrane (CAM) of a developing chick was studied by light and electron microscopy. A proteinase-producing strain, NUM961, invaded into intact CAM, but proteinase-deficient strain NUM678 cells remained on the surface of the CAM with no evidence of damage to the host cells. However, NUM678 cells invaded into the ectoderm-damaged CAM, or proteinase-treated one. Electron microscopy revealed that treatment with purified Candida proteinase disorganized the ectoderm tissue by disrupting the intercellular junctions. These results suggest that Candida proteinase damages the CAM surface, which enables the invasion of the growing hyphae.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0385-5600
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
709-19
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
A role of secreted proteinase of Candida albicans for the invasion of chick chorio-allantoic membrane.
pubmed:affiliation
Laboratory of Medical Mycology, Nagoya University School of Medicine.
pubmed:publicationType
Journal Article