Linked Life Data

2684557

Source:http://linkedlifedata.com/resource/pubmed/id/2684557

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1990-1-10
pubmed:abstractText
To determine the effects of mean airway pressure on hemodynamics during high-frequency ventilation, we ventilated five cats (wt 2.8 +/- 0.6 kg) using both HFOV (frequencies 3 to 20 Hz) and HFJV (frequencies 4 to 8 Hz) at Paw values ranging from 2 to 12 cm H2O. Combinations of frequency and tidal volume that maintained normocapnia were employed in random order before and after reduction of static compliance of the respiratory system by lung lavage. Heart rate was comparable during both modes of high-frequency ventilation. During both HFOV and HFJV, the cardiac output decreased and PVR increased in normal and surfactant-deficient cats as Paw was elevated (all p less than 0.01, ANOVA). For both HFOV and HFJV linear regression of Paw and cardiac output yielded comparable slopes and y-intercepts. Lung lavage reduced the effect of Paw but did not eliminate it. Changes in ventilatory frequency did not affect cardiac output or PVR. We conclude that the interaction between high-frequency ventilation and cardiovascular function is largely determined by Paw and compliance and is independent of ventilator frequency and the type of ventilator used.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0012-3692
pubmed:author
pubmed:issnType
Print
pubmed:volume
96
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1400-4
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Cardiovascular effects of high-frequency oscillatory and jet ventilation.
pubmed:affiliation
Department of Pediatrics and Cardiothoracic Surgery, Rainbow Babies and Childrens Hospital, Case Western Reserve University, Cleveland.
pubmed:publicationType
Journal Article