Linked Life Data

2684165

Source:http://linkedlifedata.com/resource/pubmed/id/2684165

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
19
pubmed:dateCreated
1989-11-28
pubmed:abstractText
The binding of [3H(G)]ouabain was examined in both rat pancreatic islets and tumoral islet cells (RINm5F line). In the islets, the specific binding was considered too low to allow for extensive investigations, taking into account the limited number of islets readily available. In the RINm5F cells, which bound more ouabain than normal islet cells, the time course for binding, its temperature dependency, its competitive inhibition by K+, the number of binding sites, their affinity, and the turnover of ATP per binding site were all similar to those found in other cell types. An incomplete dissociation of [3H(G)]ouabain by unlabelled glycoside and the stimulation of binding by D-glucose were noticed, both phenomena being possibly attributable, in part at least, to the functional response of the RINm5F cells to D-glucose with resulting activation of exocytosis-endocytosis coupling.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0006-2952
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3371-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Binding of ouabain to normal and tumoral pancreatic islet cells.
pubmed:affiliation
Fundacion Jimenez Diaz, Centro Asociado el Consejo Superior de Investigaciones Cientificas, Madrid, Spain.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't