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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1989-12-21
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pubmed:abstractText |
In order to examine the development of the chronic candidal lesion of the dorsal rat tongue, 210 rats were given a single oral inoculum of Candida albicans on Day 0 and were sequentially killed over a 20-wk period. Dorsal tongue changes were evaluated using clinical photographs, histologic sections and scanning electron microscopy (SEM). Clinically evident lesions became apparent at 2 wk post-inoculation, and inflammatory changes of the underlying connective tissue were observed by 3 wk post-inoculation. SEM showed a gradient of destruction of the dorsal tongue papillae at the periphery of the candidal lesions. Hyphae were seen infrequently on the lesional surface by SEM, a finding which correlated with the light microscopy.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
D
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0904-2512
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
352-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2681688-Animals,
pubmed-meshheading:2681688-Candida albicans,
pubmed-meshheading:2681688-Candidiasis, Oral,
pubmed-meshheading:2681688-Epithelium,
pubmed-meshheading:2681688-Female,
pubmed-meshheading:2681688-Glossitis,
pubmed-meshheading:2681688-Microscopy, Electron, Scanning,
pubmed-meshheading:2681688-Rats,
pubmed-meshheading:2681688-Rats, Inbred Strains,
pubmed-meshheading:2681688-Tongue
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pubmed:year |
1989
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pubmed:articleTitle |
Clinical, histologic and scanning electron microscopic study of the development of chronic candidiasis of the rat tongue.
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pubmed:affiliation |
Ohio State University College of Dentistry, Columbus 43210.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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