Linked Life Data

2681537

Source:http://linkedlifedata.com/resource/pubmed/id/2681537

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1989-12-20
pubmed:abstractText
Intricatin [1] and intricatinol [2] are new homoisoflavonoids isolated from a desert plant Hoffmanosseggia intricata, which was collected in Baja California, Mexico. The structures of the compounds were elucidated using a variety of spectroscopic techniques. The structure of 1 was shown to be 7,4'-dimethoxy-8-hydroxyhomoisoflavone, and 2 was shown to be 4'-methoxy-7,8-dihydroxyhomoisoflavone. Both compounds 1 and 2 displayed activity in the inhibition of the mutagenicity of 2AN toward Salmonella typhimurium (T98). Compound 2 was much more active than 1 in the case of the inhibition of the mutagenicity of AAF toward S. typhimurium (T98) and the inhibition of EMS towards S. typhimurium (T100). Compounds 1 and 2 are the first examples of antimutagenic activity in homoisoflavones.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0163-3864
pubmed:author
pubmed:issnType
Print
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
774-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Plant antimutagens, 6. Intricatin and intricatinol, new antimutagenic homoisoflavonoids from Hoffmanosseggia intricata.
pubmed:affiliation
Research Triangle Institute, North Carolina 27709.
pubmed:publicationType
Journal Article, In Vitro