Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1989-12-4
pubmed:abstractText
Fifty consecutive patients with non-ulcer dyspepsia and a Campylobacter associated gastritis (CAG) were randomly assigned to treatment with colloidal bismuth subcitrate (CBS) 240 mg twice daily or placebo, according to a double blind study design. After the blind treatment an 'open' treatment with CBS was started in both groups. Twenty six patients treated with CBS showed a significant reduction in colonisation with Campylobacter pylori and a significant improvement in the Whitehead gastritis score. No significant changes were recorded in twenty four patients treated with placebo. After an additional course of CBS no further improvement in gastritis score was noted but there was a further reduction in Campylobacter colonisation. CBS did not greatly alter subjective complaints. Subjective complaints were improved in both treatment groups except for nausea and meteorism that improved more in the CBS treated patients. This finding again questions the clinical significance of gastritis and also casts doubt on the clinical relevance of therapeutical measures aimed at eradication of C pylori.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/2680795-2338279, http://linkedlifedata.com/resource/pubmed/commentcorrection/2680795-2447004, http://linkedlifedata.com/resource/pubmed/commentcorrection/2680795-3092967, http://linkedlifedata.com/resource/pubmed/commentcorrection/2680795-3094652, http://linkedlifedata.com/resource/pubmed/commentcorrection/2680795-3335295, http://linkedlifedata.com/resource/pubmed/commentcorrection/2680795-342548, http://linkedlifedata.com/resource/pubmed/commentcorrection/2680795-3614058, http://linkedlifedata.com/resource/pubmed/commentcorrection/2680795-3665680, http://linkedlifedata.com/resource/pubmed/commentcorrection/2680795-3700291, http://linkedlifedata.com/resource/pubmed/commentcorrection/2680795-3721285, http://linkedlifedata.com/resource/pubmed/commentcorrection/2680795-3767346, http://linkedlifedata.com/resource/pubmed/commentcorrection/2680795-6145023, http://linkedlifedata.com/resource/pubmed/commentcorrection/2680795-6470176
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0017-5749
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1206-12
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Campylobacter associated gastritis in patients with non-ulcer dyspepsia: a double blind placebo controlled trial with colloidal bismuth subcitrate.
pubmed:affiliation
Department of Internal Medicine, University Hospital, Maastricht, The Netherlands.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial