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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
1989-11-29
|
| pubmed:abstractText |
CD4 is an MHC class II binding protein found on T cells that recognize peptide fragments of protein antigens bound to MHC class II molecules. In this review, Charlie Janeway argues that CD4 is a physical component of the T-cell receptor, and that CD4 augments signalling via the receptor by about 100-fold. He proposes the term co-receptor to describe this molecule and its functional homologue, CD8.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0167-5699
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
10
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
234-8
|
| pubmed:dateRevised |
2005-11-16
|
| pubmed:meshHeading | |
| pubmed:year |
1989
|
| pubmed:articleTitle |
The role of CD4 in T-cell activation: accessory molecule or co-receptor?
|
| pubmed:publicationType |
Journal Article,
Review
|