Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1977-9-29
pubmed:abstractText
Halothane-nitrous oxide-oxygen (GOF), nitrous oxide-oxygen with diallyl-nor-toxiferine (Jackson-Rees method), or nitrous oxide-oxygen with droperidol-pentazocine (modified NLA) were administered in 190 instances of repair of cleft lips and cleft palates. Epinephrine, 1:30,000, 1:100,000, or 1:300,000, was injected as the vasoconstrictor around the operative field. Epinephrine concentration of 1:100,000 provided sufficient hemostasis, whereas 1:300,000 was insufficient. With the same concentration of epinephrine, GOF and modified NLA seemed to be better than the Jackson-Rees method, since the GOF and modified NLA groups showed less increase of pulse rate, blood pressure, and plethysmographic changes. A 1:30,000 concentration of epinephrine could be used safely with the Jackson-Rees method and the hemostasis with this concentration was superior to 1:100,000. However, it is recommended only for the cleft lip operation, since these patients are younger and need better hemostasis, and hypersalivation after reversal does not disturb the postoperative course. So-called epinephrine-induced arrhythmia with halothane anesthesia occurred in 1 of 34 instances with 1:300,000 solution and in 5 of 48 instances with 1:100,000 solution. Propranolol was given in only one instance. All others returned to normal rhythm with hyperventilation with pure oxygen. The use of 1:100,000 solution of epinephrine as an adjunct with modified NLA is the most satisfactory and safe method for cleft palate operations, and 1:30,000 with the Jackson-Rees is the better method for cleft lip repairs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0022-3255
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
713-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:267751-Alcuronium, pubmed-meshheading:267751-Analysis of Variance, pubmed-meshheading:267751-Anesthesia, General, pubmed-meshheading:267751-Anesthetics, pubmed-meshheading:267751-Arrhythmias, Cardiac, pubmed-meshheading:267751-Atropine, pubmed-meshheading:267751-Blood Pressure, pubmed-meshheading:267751-Child, Preschool, pubmed-meshheading:267751-Diazepam, pubmed-meshheading:267751-Droperidol, pubmed-meshheading:267751-Electrocardiography, pubmed-meshheading:267751-Epinephrine, pubmed-meshheading:267751-Halothane, pubmed-meshheading:267751-Heart, pubmed-meshheading:267751-Hemodynamics, pubmed-meshheading:267751-Hemorrhage, pubmed-meshheading:267751-Hemostasis, pubmed-meshheading:267751-Humans, pubmed-meshheading:267751-Infant, pubmed-meshheading:267751-Nitrous Oxide, pubmed-meshheading:267751-Pentazocine, pubmed-meshheading:267751-Plethysmography, pubmed-meshheading:267751-Preanesthetic Medication, pubmed-meshheading:267751-Pulse
pubmed:year
1977
pubmed:articleTitle
Hemodynamic effects of locally applied epinephrine used with various general anesthetic techniques.
pubmed:publicationType
Journal Article