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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1977-9-29
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pubmed:abstractText |
Halothane-nitrous oxide-oxygen (GOF), nitrous oxide-oxygen with diallyl-nor-toxiferine (Jackson-Rees method), or nitrous oxide-oxygen with droperidol-pentazocine (modified NLA) were administered in 190 instances of repair of cleft lips and cleft palates. Epinephrine, 1:30,000, 1:100,000, or 1:300,000, was injected as the vasoconstrictor around the operative field. Epinephrine concentration of 1:100,000 provided sufficient hemostasis, whereas 1:300,000 was insufficient. With the same concentration of epinephrine, GOF and modified NLA seemed to be better than the Jackson-Rees method, since the GOF and modified NLA groups showed less increase of pulse rate, blood pressure, and plethysmographic changes. A 1:30,000 concentration of epinephrine could be used safely with the Jackson-Rees method and the hemostasis with this concentration was superior to 1:100,000. However, it is recommended only for the cleft lip operation, since these patients are younger and need better hemostasis, and hypersalivation after reversal does not disturb the postoperative course. So-called epinephrine-induced arrhythmia with halothane anesthesia occurred in 1 of 34 instances with 1:300,000 solution and in 5 of 48 instances with 1:100,000 solution. Propranolol was given in only one instance. All others returned to normal rhythm with hyperventilation with pure oxygen. The use of 1:100,000 solution of epinephrine as an adjunct with modified NLA is the most satisfactory and safe method for cleft palate operations, and 1:30,000 with the Jackson-Rees is the better method for cleft lip repairs.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Alcuronium,
http://linkedlifedata.com/resource/pubmed/chemical/Anesthetics,
http://linkedlifedata.com/resource/pubmed/chemical/Atropine,
http://linkedlifedata.com/resource/pubmed/chemical/Diazepam,
http://linkedlifedata.com/resource/pubmed/chemical/Droperidol,
http://linkedlifedata.com/resource/pubmed/chemical/Epinephrine,
http://linkedlifedata.com/resource/pubmed/chemical/Halothane,
http://linkedlifedata.com/resource/pubmed/chemical/Nitrous Oxide,
http://linkedlifedata.com/resource/pubmed/chemical/Pentazocine
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-3255
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
713-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:267751-Alcuronium,
pubmed-meshheading:267751-Analysis of Variance,
pubmed-meshheading:267751-Anesthesia, General,
pubmed-meshheading:267751-Anesthetics,
pubmed-meshheading:267751-Arrhythmias, Cardiac,
pubmed-meshheading:267751-Atropine,
pubmed-meshheading:267751-Blood Pressure,
pubmed-meshheading:267751-Child, Preschool,
pubmed-meshheading:267751-Diazepam,
pubmed-meshheading:267751-Droperidol,
pubmed-meshheading:267751-Electrocardiography,
pubmed-meshheading:267751-Epinephrine,
pubmed-meshheading:267751-Halothane,
pubmed-meshheading:267751-Heart,
pubmed-meshheading:267751-Hemodynamics,
pubmed-meshheading:267751-Hemorrhage,
pubmed-meshheading:267751-Hemostasis,
pubmed-meshheading:267751-Humans,
pubmed-meshheading:267751-Infant,
pubmed-meshheading:267751-Nitrous Oxide,
pubmed-meshheading:267751-Pentazocine,
pubmed-meshheading:267751-Plethysmography,
pubmed-meshheading:267751-Preanesthetic Medication,
pubmed-meshheading:267751-Pulse
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pubmed:year |
1977
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pubmed:articleTitle |
Hemodynamic effects of locally applied epinephrine used with various general anesthetic techniques.
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pubmed:publicationType |
Journal Article
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