Linked Life Data

2674633

Source:http://linkedlifedata.com/resource/pubmed/id/2674633

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1989-10-23
pubmed:abstractText
A seroepidemiological survey was carried out with the aim of establishing whether or not HIV 2 infection could be detected in Western Sicily. Two groups of sera were tested by EIA and WB assay against HIV 1 and HIV 2. 200 sera taken from North African immigrants in the Mazara del Vallo area, and 297 samples taken from AIDS-high risk groups individuals living in Palermo. None of the North African sera was positive to HIV 1 and/or HIV 2 by either techniques. 118 of the 297 sera from Palermo were HIV 1 positive by both techniques; 69 thereof also reacted to HIV 2 by EIA. Only six of these were confirmed by WB assay, showing a clear reactivity against the 140 and 105 HIV 2 glycoproteins. However, all six sera were considered merely cross-reactive to HIV 2, since none of them had neutralizing antibody to HIV 2 and the cross reactivity to glycoproteins of HIV 2 could be removed by absorbing them with HIV 1 infected cells. It seems therefore that HIV 2 has not yet reached our area. Early detection of the possible presence of this virus in our country could be obtained by improving both the surveillance and the effectiveness of laboratory tools for HIV 2 diagnosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0391-5352
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
195-201
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
No evidence of HIV 2 infection in Sicily.
pubmed:affiliation
Istituto di Igiene G. D'Alessandro, Università degli Studi, Palermo, Italy.
pubmed:publicationType
Journal Article