Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1989-10-23
pubmed:abstractText
The amino-acid sequence of pancreatic ribonuclease from the chromosomal species of Spalax ehrenbergi with karyotype 2n = 60 was determined. From the comparison of the sequence with other mammalian sequences we found that Spalax diverged from the myomorph rodent branch before the divergence of the Muridae and the Cricetidae. All myomorph rodent sequences evolved faster than those of other mammals, an effect being most pronounced for the rat sequence. Spalax ribonuclease shares several amino-acid residues with other myomorph rodent species. These are not or only rarely observed outside this rodent suborder. However, there are 6 amino-acid replacements not observed earlier in pancreatic ribonucleases, and 2 other replacements and an insertion of one residue in the variable loop 15-24 are only observed in the enzyme from turtle pancreas.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0177-3593
pubmed:author
pubmed:issnType
Print
pubmed:volume
370
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
583-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
The amino-acid sequence of pancreatic ribonuclease from the mole rat Spalax ehrenbergi, chromosomal species 2n = 60.
pubmed:affiliation
Biochemisch Laboratorium, Rijksuniversiteit Groningen.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't