Linked Life Data

2670297

Source:http://linkedlifedata.com/resource/pubmed/id/2670297

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1989-9-27
pubmed:abstractText
In order to determine the descriptive epidemiology of persistent diarrhoea in rural northern India, a cohort of 963 children aged 0-71 months was followed prospectively for 12 months through weekly household visits. The incidence of persistent diarrhoea was 6.3 per 100 child-years among those aged 0-71 months, and was highest (31 per 100 child-years) among those aged 0-11 months. There were no significant sex-related differences in the incidence of the disease, and the overall seasonal distribution of acute and persistent diarrhoea was similar. The persistence of diarrhoeal symptoms was significantly correlated with a higher initial mean stool frequency (P less than 0.01) and passage of gross blood with stools (P less than 0.001). Persistent diarrhoea was an important problem among children during the first 2 years of life. Established enteric pathogens were isolated during the initial illness in 46.4% of persistent and 55.4% of acute episodes. Pathogens isolated during persistent episodes included enterotoxigenic Escherichia coli (ETEC 9.3%), Salmonella spp. (4.7%), as well as campylobacter (4.7%), Shigella spp. (2.3%), Entamoeba histolytica (2.3%), and rotavirus (2.3%). Similar proportions of these pathogens were isolated also during episodes of acute diarrhoea. Multiple pathogens were isolated in 7% of the persistent and 5% of the acute episodes. E. coli that manifested aggregative adherence (EAEC-A) was more common (34.9% versus 12.3%) in persistent than acute episodes (P less than 0.01), and initial faecal excretion of EAEC-A was significantly associated with the persistence of a diarrhoeal episode.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-2837717, http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-2863318, http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-2863319, http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-2899125, http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-3298451, http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-3525699, http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-3766849, http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-379039, http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-3794909, http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-3882849, http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-5644749, http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-579080, http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-6278925, http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-6374599, http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-6377439, http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-7062877, http://linkedlifedata.com/resource/pubmed/commentcorrection/2670297-998219
pubmed:keyword
http://linkedlifedata.com/resource/pubmed/keyword/Age Distribution, http://linkedlifedata.com/resource/pubmed/keyword/Age Factors, http://linkedlifedata.com/resource/pubmed/keyword/Asia, http://linkedlifedata.com/resource/pubmed/keyword/DIARRHEA, http://linkedlifedata.com/resource/pubmed/keyword/Data Analysis, http://linkedlifedata.com/resource/pubmed/keyword/Data Collection, http://linkedlifedata.com/resource/pubmed/keyword/Delivery Of Health Care, http://linkedlifedata.com/resource/pubmed/keyword/Demographic Factors, http://linkedlifedata.com/resource/pubmed/keyword/Developing Countries, http://linkedlifedata.com/resource/pubmed/keyword/Diarrhea, Infantile--etiology, http://linkedlifedata.com/resource/pubmed/keyword/Diseases, http://linkedlifedata.com/resource/pubmed/keyword/Epidemiologic Methods, http://linkedlifedata.com/resource/pubmed/keyword/Examinations And Diagnoses, http://linkedlifedata.com/resource/pubmed/keyword/Health, http://linkedlifedata.com/resource/pubmed/keyword/Health Services, http://linkedlifedata.com/resource/pubmed/keyword/INDIA, http://linkedlifedata.com/resource/pubmed/keyword/Incidence, http://linkedlifedata.com/resource/pubmed/keyword/Laboratory Examinations And Diagnoses, http://linkedlifedata.com/resource/pubmed/keyword/Measurement, http://linkedlifedata.com/resource/pubmed/keyword/Population, http://linkedlifedata.com/resource/pubmed/keyword/Population Characteristics, http://linkedlifedata.com/resource/pubmed/keyword/Primary Health Care, http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology, http://linkedlifedata.com/resource/pubmed/keyword/Rural Population, http://linkedlifedata.com/resource/pubmed/keyword/Southern Asia
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0042-9686
pubmed:author
pubmed:issnType
Print
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
281-8
pubmed:dateRevised
2009-11-18
pubmed:otherAbstract
PIP: In order to determine the descriptive epidemiology of persistent diarrhea in rural northern India, a cohort of 963 children ages 0-71 months was followed prospectively for 12 months through weekly household visits. The incidence of persistent diarrhea was 6.3/100 child-years among those ages 0-7 months, and was highest (31/100 child-years) among those ages 0-11 months. There were no significant sex-related differences in the incidence of the disease, and the overall seasonal distribution of acute and persistent diarrhea was similar. The persistence of diarrheal symptoms was significantly correlated with a higher initial mean stool frequency (p0.01) and passage of gross blood with tools (p0.001). Persistent diarrhea was an important problem among children during the 1st 2 years of life. Established enteric pathogens were isolated during the initial illness in 46.4% of persistent and 55.4% of acute episodes. Pathogens isolated during persistent episodes included enterotoxigenic Escherichia ecoli (ETEC 9.3%), Salmonella spp. (4.7%), as well as campylobacter (4.7%), Shigella spp. (2.3%), Entamoeba histolytica (2.3%), and rotavirus (2.3%). Similar proportions of these pathogens were isolated also during episodes of acute diarrhea. Multiple pathogens were isolated in 7% of the persistent and 5% of the acute episodes. E. coli that manifested aggregative adherence (EAEC-A) was more common (34.9% vs 12.3%) in persistent than acute episodes (p0.01), and initial fecal excretion of EAEC-A was significantly associated with the persistence of a diarrheal episode. (author's)
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Descriptive epidemiology of persistent diarrhoea among young children in rural northern India.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't