Linked Life Data

2669295

Source:http://linkedlifedata.com/resource/pubmed/id/2669295

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1989-9-12
pubmed:abstractText
Macrophages are large mononuclear phagocytes that represent the major differentiated elements of the mononuclear phagocytic system. They arise from distinct progenitors in the bone marrow, and their immediate precursors, the monocytes, emigrate from the vascular compartment into many tissues and organs where they develop into mature macrophages. The latter display diverse morphological and functional characteristics, depending on the environmental stimuli that they receive. This phenotypic heterogeneity is, therefore, the final consequence of a series of down-regulation of some cellular processes and the up-regulation of others. The kinetics of the production of macrophages and their participation in various physiological and pathological phenomena is the subject of this review.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0191-3123
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
343-72
pubmed:dateRevised
2009-6-26
pubmed:meshHeading
pubmed:articleTitle
Macrophages: current views on their differentiation, structure, and function.
pubmed:affiliation
Department of Pathology, University of Western Australia, Nedlands.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't