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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1977-7-29
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pubmed:abstractText |
At high ionic strength (e.g., physiological salt concentrations) chromosome fibers are 200 A in diameter and composed of discrete globular structures that are held together by histone H1. At low ionic strength the fibers unfold and appear as the familiar chains of nucleosomes (80 A in diameter). The unfolding of chromosome fibers occurs within a narrow salt range. It results from a change in the mode of the interaction between histone H1 and the chromosome fiber and is very likely the consequence of a change from cooperative binding between histone H1 and DNA to a noncooperative binding. In the noncooperative binding state histone H1 molecules are randomly redistributed along the chromosome fiber.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-1064861,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-10793713,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-1095754,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-1167623,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-1175645,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-13375653,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-14480271,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-4128918,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-4573844,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-4634354,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-4825889,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-5050359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-5102527,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-5116611,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-5432063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-6006604,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-782515,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-964366,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-967672,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-972173,
http://linkedlifedata.com/resource/pubmed/commentcorrection/266711-986286
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0027-8424
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
74
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1879-83
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:266711-Animals,
pubmed-meshheading:266711-Binding Sites,
pubmed-meshheading:266711-Chromosomes,
pubmed-meshheading:266711-Histones,
pubmed-meshheading:266711-Humans,
pubmed-meshheading:266711-Lymphocytes,
pubmed-meshheading:266711-Microscopy, Electron,
pubmed-meshheading:266711-Middle Aged,
pubmed-meshheading:266711-Molecular Weight,
pubmed-meshheading:266711-Osmolar Concentration,
pubmed-meshheading:266711-Sodium Chloride
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pubmed:year |
1977
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pubmed:articleTitle |
Involvement of histone H1 in the organization of the chromosome fiber.
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pubmed:publicationType |
Journal Article
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