Linked Life Data

2666601

Source:http://linkedlifedata.com/resource/pubmed/id/2666601

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1989-8-31
pubmed:abstractText
Evidence for the influence of trace elements on disease resistance in ruminants is reviewed with emphasis on susceptibility to infection in vivo during the more common deficiencies (copper, selenium and cobalt). Copper deficiency associated with increases in pasture molybdenum increased the susceptibility of lambs to microbial infections. Under experimental conditions, dietary molybdenum decreased the establishment of abomasal and intestinal nematodes but not their pathogenicity to lambs. Molybdenum may enhance inflammatory responses leading to parasite rejection by the host. Decreased incidence of metritis in selenium-treated dairy cows provides a rare example of an association between selenium deficiency and decreased disease resistance. Improved antibody responses following selenium administration have also been found in sheep. Cobalt deficiency has reduced lamb survival and increased susceptibility to parasitic infection transiently in cattle and lastingly in sheep. In copper-, selenium- or cobalt-deficient sheep and cattle, there are many reports of impaired leucocyte and lymphocyte responses to in vitro challenges, but their relevance to disease resistance in vivo is unproven. Disease resistance may have priority for limited micronutrient supplies, leaving other processes vulnerable.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0022-3166
pubmed:author
pubmed:issnType
Print
pubmed:volume
119
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1055-61
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Recent developments in trace element metabolism and function: trace elements, disease resistance and immune responsiveness in ruminants.
pubmed:affiliation
Moredun Research Institute, Edinburgh, Scotland.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't