Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1989-8-25
|
pubmed:abstractText |
The lipid-associated sialic acid (LASA) level in serum was increased in 663 out of 794 patients (83.5%) of which 55.1% were CEA negative. There were 16.5% LASA (possibly false) negative, CEA positive patients. There were 24.1% false positives in 116 patients without malignant tumors. In manifest prostatic carcinoma 94.2% of the LASA values but only 36.5% of the prostatic acid phosphatase values were increased. Similarly, in breast and pulmonary carcinoma, LASA was more sensitive than CEA. In 499 patients with minimal residual disease, 203 (41.5%) were LASA-negative, of which 180 were CEA-negative. Out of 180 LASA positive patients, 70 have relapsed, as have 70 out of 219 patients with increases in both LASA and CEA. The sensitivity of LASA (87%) in lymphoma was higher than that of the erythrocyte sedimentation rate (53.3%), of C-reactive protein (51.2%), serum copper (64.7%) and of six other markers.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Carcinoembryonic Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Lipids,
http://linkedlifedata.com/resource/pubmed/chemical/N-Acetylneuraminic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Sialic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/lipid-associated sialic acid
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0037-9247
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
126
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
17-20
|
pubmed:dateRevised |
2008-5-30
|
pubmed:meshHeading |
pubmed-meshheading:2663215-Carcinoembryonic Antigen,
pubmed-meshheading:2663215-Female,
pubmed-meshheading:2663215-Humans,
pubmed-meshheading:2663215-Lipids,
pubmed-meshheading:2663215-Male,
pubmed-meshheading:2663215-N-Acetylneuraminic Acid,
pubmed-meshheading:2663215-Neoplasms,
pubmed-meshheading:2663215-Sensitivity and Specificity,
pubmed-meshheading:2663215-Sialic Acids,
pubmed-meshheading:2663215-Tumor Markers, Biological
|
pubmed:articleTitle |
Serum lipid-bound sialic acid as a tumoral marker in minimal residual tumors.
|
pubmed:publicationType |
Journal Article,
Duplicate Publication
|