Linked Life Data

2663025

Source:http://linkedlifedata.com/resource/pubmed/id/2663025

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1989-8-14
pubmed:abstractText
Liver transplantation has become an accepted therapeutic modality for many patients with end-stage liver diseases. Compared to other solid organ allografts, the immunopathological mechanisms involved in the original disease, rejection reactions, and potentially recurrent original diseases are seemingly more complex. The spontaneous acceptance of animal liver grafts without immunosuppression, the induction of donor-specific tolerance after liver grafting, its seeming resistance to hyperacute or primary humoral rejection, the dualistic effect of major histocompatibility matching on graft survival, functional and immunohistopathologic aspects of rejection reactions, infections, and the complexities involved in analysis for the potential of recurrent disease are discussed. Although many issues remain unresolved, liver transplantation offers a unique opportunity for studying the role of the immune system in both transplantation biology and primary liver disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1040-8401
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
67-92
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Immunopathology of liver transplantation.
pubmed:affiliation
Department of Pathology, University of Pittsburgh, Pennsylvania.
pubmed:publicationType
Journal Article, Review