Linked Life Data

2661334

Source:http://linkedlifedata.com/resource/pubmed/id/2661334

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1989-8-3
pubmed:abstractText
The crystalline lens absorbs most of the incident UV radiation between 300 and 400 nm and thereby protects the retina from a significant, potential source of photochemical damage. This protection is lost when the lens is removed by cataract surgery, but can be restored by the implantation of an intraocular lens (IOL) that has UV-absorbing chromophores incorporated into a polymethylmethacrylate (PMMA) substrate. Spectrophotometric data show that the various, commercially available, UV-absorbing IOLs are not equally effective in absorbing UV radiation; thus, a standard, quantitative metric for comparing their performance is proposed. Cytotoxicity and biocompatibility studies have failed to demonstrate that UV-absorbing IOLs are unsafe, even when damaged by Nd:YAG lasers used for photodiscission posterior capsulotomy. There are positive consequences for the pseudophakic patient with a UV-absorbing IOL, in that it may restore normal spectral sensitivity, reduce erythropsia and cystoid macular edema, and stabilize the blood-vitreous barrier.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0721-832X
pubmed:author
pubmed:issnType
Print
pubmed:volume
227
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
248-56
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
UV-absorbing intraocular lenses: safety, efficacy, and consequences for the cataract patient.
pubmed:affiliation
Department of Psychology, University of Colorado, Boulder 80309.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't