Linked Life Data

265951

Source:http://linkedlifedata.com/resource/pubmed/id/265951

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1977-6-30
pubmed:abstractText
This investigation describes a simple and effective method of antibiotic suppression of the total indigenous microbiol flora of rats. Specifically, the results of this study demonstrate that: (1) antibiotics which inhibit microbial growth of oral and fecal cultures from individual rats are effective in suppressing the indigenous flora of 95% of these rats when provided as dietary supplements; (2) S mutans 6715 colonized 95% of the antibiotic-suppressed animals while only 50% of the untreated rat pups yielded S mutans following challenge with a single inoculum of this micro-organism; and (3) significant smooth surface caries developed in S mutans-infected rats within 20 days when provided caries-promoting Diet 305, while noninfected, antibiotic-suppppressed offspring remained essentially caries-free.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0022-0345
pubmed:author
pubmed:issnType
Print
pubmed:volume
56
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
205-11
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Virulence of Streptococcus mutans: an antibiotic-suppressed rat model for studies of pathogenesis.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.