| pubmed-article:2659507 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2659507 | lifeskim:mentions | umls-concept:C0021757 | lld:lifeskim |
| pubmed-article:2659507 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
| pubmed-article:2659507 | lifeskim:mentions | umls-concept:C0079490 | lld:lifeskim |
| pubmed-article:2659507 | lifeskim:mentions | umls-concept:C1334117 | lld:lifeskim |
| pubmed-article:2659507 | lifeskim:mentions | umls-concept:C1441547 | lld:lifeskim |
| pubmed-article:2659507 | pubmed:issue | 1-4 | lld:pubmed |
| pubmed-article:2659507 | pubmed:dateCreated | 1989-7-18 | lld:pubmed |
| pubmed-article:2659507 | pubmed:abstractText | The present study was undertaken to elucidate the effect of bacterial lipopolysaccharides (LPS) on B lymphocyte derived hematopoietic growth factors. Bone marrow-derived (BM) B cells and homogeneous B cell lines (lymphomas and hybridomas) were used to study the production of granulocyte-macrophage colony stimulating factor (GM-CSF). The BM B cells required two signals for GM-CSF production: LPS and a tumor promoting phorbol ester (TPA). In the B cell lines, GM-CSF production was inducible with LPS alone. Molecular analysis of the GM-CSF gene expression revealed that steady state levels (as determined by Northern analysis) of GM-CSF mRNA could be detected only in LPS-induced cells, whereas it was found by nuclear transcription analysis that the GM-CSF gene is transcribed even in uninduced cells. However, biological activity of GM-CSF was detected only in supernatants from LPS-induced cells. These data suggest a post-transcriptional regulation of this gene. | lld:pubmed |
| pubmed-article:2659507 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2659507 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2659507 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2659507 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2659507 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2659507 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2659507 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2659507 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2659507 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2659507 | pubmed:issn | 0882-0139 | lld:pubmed |
| pubmed-article:2659507 | pubmed:author | pubmed-author:MergenhagenS... | lld:pubmed |
| pubmed-article:2659507 | pubmed:author | pubmed-author:BickelMM | lld:pubmed |
| pubmed-article:2659507 | pubmed:author | pubmed-author:PluznikD HDH | lld:pubmed |
| pubmed-article:2659507 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2659507 | pubmed:volume | 18 | lld:pubmed |
| pubmed-article:2659507 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2659507 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2659507 | pubmed:pagination | 103-16 | lld:pubmed |
| pubmed-article:2659507 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2659507 | pubmed:meshHeading | pubmed-meshheading:2659507-... | lld:pubmed |
| pubmed-article:2659507 | pubmed:meshHeading | pubmed-meshheading:2659507-... | lld:pubmed |
| pubmed-article:2659507 | pubmed:meshHeading | pubmed-meshheading:2659507-... | lld:pubmed |
| pubmed-article:2659507 | pubmed:meshHeading | pubmed-meshheading:2659507-... | lld:pubmed |
| pubmed-article:2659507 | pubmed:meshHeading | pubmed-meshheading:2659507-... | lld:pubmed |
| pubmed-article:2659507 | pubmed:meshHeading | pubmed-meshheading:2659507-... | lld:pubmed |
| pubmed-article:2659507 | pubmed:meshHeading | pubmed-meshheading:2659507-... | lld:pubmed |
| pubmed-article:2659507 | pubmed:meshHeading | pubmed-meshheading:2659507-... | lld:pubmed |
| pubmed-article:2659507 | pubmed:meshHeading | pubmed-meshheading:2659507-... | lld:pubmed |
| pubmed-article:2659507 | pubmed:meshHeading | pubmed-meshheading:2659507-... | lld:pubmed |
| pubmed-article:2659507 | pubmed:meshHeading | pubmed-meshheading:2659507-... | lld:pubmed |
| pubmed-article:2659507 | pubmed:meshHeading | pubmed-meshheading:2659507-... | lld:pubmed |
| pubmed-article:2659507 | pubmed:articleTitle | B lymphocyte derived hematopoietic growth factors. | lld:pubmed |
| pubmed-article:2659507 | pubmed:affiliation | Laboratory of Immunology, National Institute of Dental Research, Bethesda, MD 20892. | lld:pubmed |
| pubmed-article:2659507 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2659507 | pubmed:publicationType | In Vitro | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2659507 | lld:pubmed |
