Linked Life Data

2658702

Source:http://linkedlifedata.com/resource/pubmed/id/2658702

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1989-7-12
pubmed:abstractText
This study reviews the relationship between body weight, pulmonary function, and survival in the recent clinical trial of intermittent positive pressure breathing (IPPB). We related body weight, expressed as a percent of the ideal (%IBW), to the numerous other features of the disease recorded in this data set. Body weight was directly related to FEV1 (p = 0.0001), so that all subsequent analyses of body weight had to first consider FEV1. Mortality appeared to be influenced by body weight independent of FEV1. In patients with %FEV1 less than 35, mortality increased with decreasing body weight (p = 0.093), and this relationship was stronger in patients with %FEV1 35 to 47 (p = 0.048) and even stronger in patients with %FEV1 greater than 47 (p = 0.007). After adjusting for FEV1, body weight was a powerful positive correlate with exercise capacity (p = 0.0001). Body weight was also inversely related to %TLC (p = 0.0408) after adjusting for FEV1. Body weight was a powerful predictor of diffusing capacity (p = 0.0001) in patients with the same FEV1. These results support the hypothesis that factors related to nutritional status are an independent influence on the course of COPD.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0003-0805
pubmed:author
pubmed:issnType
Print
pubmed:volume
139
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1435-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Body weight in chronic obstructive pulmonary disease. The National Institutes of Health Intermittent Positive-Pressure Breathing Trial.
pubmed:affiliation
Department of Medicine, University of Pittsburgh, Pennsylvania.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't