Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-6-1
pubmed:abstractText
Thirteen patients who received liver transplants at the National Liver Transplant Unit between January 1986 and March 1987 were studied with extensive monitoring and frequent intraoperative biochemical and haematological profiles. Anaesthetic technique was standardised for all patients. Retrospective analysis of this data confirms that patient homeostasis is most disturbed at the time of revascularisation of the donor liver. In this series, revascularisation was associated with marked changes in all measured haemodynamic parameters (arterial blood pressure, cardiac index, heart rate, and filling pressures). There was also a significant fall in pH with revascularisation, followed by a gradual rise during the final phases of the operation. Potassium levels often rose sharply with revascularisation but then decreased during the rest of the operative period. Ionised calcium levels did not change significantly at any stage; however, all patients were given calcium intraoperatively. Coagulation profiles were often abnormal preoperatively. The transplant procedure was associated with further abnormalities in both coagulation and fibrinolysis. Patient temperatures were maintained at normal levels throughout the procedure.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0310-057X
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
24-30
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Physiological changes during liver transplantation.
pubmed:affiliation
Liver Transplant Unit, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
pubmed:publicationType
Journal Article