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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1989-6-7
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pubmed:abstractText |
In vitro 14-day cultures of bone marrow from a patient with dyskeratosis congenita showed virtually no growth of colonies. The addition of recombinant granulocyte-macrophage colony stimulating factor (rGM-CSF) promoted a significant increase in the number of GM colonies (CFU-GM). Interleukin 3 also increased GM colony formation but to a lesser extent. GM-CSF may have a therapeutic implication for pancytopenia in dyskeratosis congenita.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0021-2180
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
193-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2651350-Adult,
pubmed-meshheading:2651350-Bone Marrow,
pubmed-meshheading:2651350-Cells, Cultured,
pubmed-meshheading:2651350-Colony-Stimulating Factors,
pubmed-meshheading:2651350-Granulocyte-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:2651350-Growth Substances,
pubmed-meshheading:2651350-Hematopoietic Stem Cells,
pubmed-meshheading:2651350-Humans,
pubmed-meshheading:2651350-Leukoplakia, Oral,
pubmed-meshheading:2651350-Male,
pubmed-meshheading:2651350-Nails, Malformed,
pubmed-meshheading:2651350-Pancytopenia,
pubmed-meshheading:2651350-Pigmentation Disorders,
pubmed-meshheading:2651350-Syndrome,
pubmed-meshheading:2651350-Tongue Neoplasms
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pubmed:year |
1989
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pubmed:articleTitle |
Granulocytic macrophage colony stimulating factor restores in vitro growth of granulocyte-macrophage bone marrow hematopoietic progenitors in dyskeratosis congenita.
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pubmed:affiliation |
Institute of Hematology, Ichilov Hospital, Tel Aviv Medical Center, Israel.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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