Linked Life Data

2651060

Source:http://linkedlifedata.com/resource/pubmed/id/2651060

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
16
pubmed:dateCreated
1989-5-30
pubmed:abstractText
The time of acute myocardial infarction (MI) was determined from the onset of symptoms and an analysis made of the time-activity course of the plasma CK-MB isoenzyme in 1741 patients of the prospective multicentre ISAM study (much greater than Intravenous Streptokinase in Acute Myocardial Infarction much less than). The occurrence of MI had a circadian variation with a marked peak between 6 a.m. and 12 noon compared with other periods during the day (P less than 0.001). Between 8 and 9 a.m., the period of highest incidence, the number of MIs was about four times higher than between midnight and 1 am (the period of lowest incidence). There was a good correlation between the clinical and enzymatic criteria for onset of MI (r = 0.95; P less than 0.001). A similar circadian pattern was obtained independent of site of MI, age and sex of patients, as well as severity and extent of the coronary heart disease. The temporal relationship between increased incidence of acute coronary heart disease (MI, sudden cardiac death, symptomatic or silent myocardial ischaemia) in the morning and a rise in platelet aggregation in the morning may point to a causal relationship.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0012-0472
pubmed:author
pubmed:issnType
Print
pubmed:day
21
pubmed:volume
114
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
613-7
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Circadian variation in the incidence of myocardial infarction. New perceptions about the mechanisms of acute coronary disease].
pubmed:affiliation
Abteilung für Kardiologie Pulmologie, Klinikum Steglitz, Freie Universität Berlin.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, English Abstract, Multicenter Study