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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1989-5-31
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pubmed:abstractText |
Naproxen was compared with placebo in a double-blind, crossover trial in classic and common migraine. The trial was terminated at a fixed date; 37 patients had entered, 5 of whom were excluded. Naproxen was given as 750 mg at the first symptom of the attack, a total of 1250 mg per 24 h was allowed. Patients were followed for six attacks or three months in each phase, whichever came first. The severity of the headache was significantly less with naproxen in the first 2 h of the attack (p = 0.047), whereas there was no difference when the whole attack was considered. Significantly more patients preferred naproxen (p = 0.042). Side effects occurred in five patients, causing withdrawal of one patient while on naproxen.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0333-1024
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
29-32
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pubmed:dateRevised |
2008-2-11
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pubmed:meshHeading |
pubmed-meshheading:2650879-Acute Disease,
pubmed-meshheading:2650879-Clinical Trials as Topic,
pubmed-meshheading:2650879-Double-Blind Method,
pubmed-meshheading:2650879-Humans,
pubmed-meshheading:2650879-Migraine Disorders,
pubmed-meshheading:2650879-Naproxen,
pubmed-meshheading:2650879-Placebos,
pubmed-meshheading:2650879-Stomach Diseases
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pubmed:year |
1989
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pubmed:articleTitle |
Double-blind study of naproxen vs placebo in the treatment of acute migraine attacks.
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pubmed:affiliation |
Department of Neuromedicine, Hjørring Sygehus, Denmark.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial
|