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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1989-4-20
|
| pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/Biology,
http://linkedlifedata.com/resource/pubmed/keyword/Contraception,
http://linkedlifedata.com/resource/pubmed/keyword/Contraception Research,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Agents,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Agents, Male,
http://linkedlifedata.com/resource/pubmed/keyword/Endocrine System,
http://linkedlifedata.com/resource/pubmed/keyword/Family Planning,
http://linkedlifedata.com/resource/pubmed/keyword/Gonadotropins,
http://linkedlifedata.com/resource/pubmed/keyword/Hormones,
http://linkedlifedata.com/resource/pubmed/keyword/Male Contraception,
http://linkedlifedata.com/resource/pubmed/keyword/Philosophical Overview,
http://linkedlifedata.com/resource/pubmed/keyword/Physiology,
http://linkedlifedata.com/resource/pubmed/keyword/Spermatogenesis Blocking Agents
|
| pubmed:language |
ger
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0044-2178
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
83
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
5-9
|
| pubmed:dateRevised |
2005-11-16
|
| pubmed:otherAbstract |
PIP: Representatives of the feminist movement have argued with increasing emphasis that the man should bear responsibility for contraception equal to the responsibility of the woman. From the endocrinological point of view, however, hormonal contraception is quite different for men. It is in principle simpler to interrupt a cyclic phenomenon such as ovulation than it is to stop the continual production of million of spermatozoa which are always available for impregnation. This constant production of spermatozoa depends upon constant stimulation by gonadotropins, and much higher doses of steroids are required than are for prevention of ovulation. In the man the basal gonadotropin secretion must be suppressed by high doses of hormone; in the woman it is sufficient to suppress the spikes in gonadotropin secretion. Luteinizing hormone, follicle stimulating hormone and prolactin all play a role in the synthesis of testosterone. Several approaches to hormonal contraception have been suggested, including suppression of gonadotropin secretion at the hypothalamus-pituitary level by sexual steroids, by direct influence on spermatogenesis by suppressing individual steps in the development or by inhibition of spermatic ripening in the epididymis. Animal experiments have demonstrated that an immunological approach against luteinizing hormone can interrupt spermatogenesis, but since steroid synthesis would also be affected, this approach must await isolation and characterization of the specific mechanism of inhibition.
|
| pubmed:meshHeading | |
| pubmed:year |
1989
|
| pubmed:articleTitle |
[Hormonal contraception in the male].
|
| pubmed:affiliation |
Frauenklinik, Städtischen Krankenhauses im Friedrichshain, Berlin.
|
| pubmed:publicationType |
Journal Article,
English Abstract,
Review
|