2645451

Source:http://linkedlifedata.com/resource/pubmed/id/2645451

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0036668, umls-concept:C0162340, umls-concept:C0205210, umls-concept:C0348026
pubmed:issue	11
pubmed:dateCreated	1989-3-31
pubmed:abstractText	Published studies encompassing more than 50,000 autopsies were assessed to determine the sensitivity and specificity of clinical diagnostics (the diagnostic process) in persons dying of 1 of 11 specific diseases during the period 1930 through 1977. The accuracy of clinical diagnostics, as reflected in these two determinations, appeared to improve over this period with respect to some of the diseases studied (rheumatic heart disease and leukemia), while for others it worsened (pulmonary tuberculosis, peritonitis, carcinoma of the lung, gastric carcinoma, and carcinoma of the liver and extrahepatic biliary tract) and for a significant number diagnostic accuracy seemed refractory to sustained change (pulmonary embolism, primary cirrhosis of the liver, gastric/peptic ulcer, and acute coronary thrombosis/myocardial infarction). The findings suggest a new way in which the autopsy can be used to monitor clinical diagnostics to identify possible sources of systematic weaknesses and provide data that can be used to approach the difficult subject of necessary fallibility.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/2645451-2739031
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7501160
pubmed:citationSubset	AIM
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	0098-7484
pubmed:author	pubmed-author:AndersonR ERE, pubmed-author:HillR BRB, pubmed-author:KeyC RCR
pubmed:issnType	Print
pubmed:day	17
pubmed:volume	261
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1610-7
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:2645451-Autopsy, pubmed-meshheading:2645451-Diagnostic Errors, pubmed-meshheading:2645451-Humans, pubmed-meshheading:2645451-Sensitivity and Specificity, pubmed-meshheading:2645451-Time Factors
pubmed:year	1989
pubmed:articleTitle	The sensitivity and specificity of clinical diagnostics during five decades. Toward an understanding of necessary fallibility.
pubmed:affiliation	Department of Pathology, University of New Mexico School of Medicine, Albuquerque, NM 87131.
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Review, Research Support, Non-U.S. Gov't