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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1989-2-7
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pubmed:abstractText |
We have established an interleukin 2-dependent, OKT4-positive T-cell line, named HCT-1, from cells in the cerebrospinal fluid obtained from a patient with human T-cell lymphotropic virus type I (HTLV-1)-associated myelopathy. Antigens for HTLV-I were detected in HCT-1 cells by indirect immunofluorescence and Western blot testing, and type C virus particles were detected by electron microscopy. Southern blot analysis of HCT-1 cellular DNA, using an HTLV-I probe, revealed that the integrated provirus genome could not be distinguished from the HTLV-I genome in adult patients with T-cell leukemia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0003-9942
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
46
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
35-7
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2642698-Blotting, Southern,
pubmed-meshheading:2642698-Blotting, Western,
pubmed-meshheading:2642698-Cell Line,
pubmed-meshheading:2642698-DNA Probes,
pubmed-meshheading:2642698-Fluorescent Antibody Technique,
pubmed-meshheading:2642698-HTLV-I Antigens,
pubmed-meshheading:2642698-HTLV-I Infections,
pubmed-meshheading:2642698-Human T-lymphotropic virus 1,
pubmed-meshheading:2642698-Humans,
pubmed-meshheading:2642698-Male,
pubmed-meshheading:2642698-Microscopy, Electron,
pubmed-meshheading:2642698-Middle Aged,
pubmed-meshheading:2642698-Spinal Cord Diseases,
pubmed-meshheading:2642698-T-Lymphocytes,
pubmed-meshheading:2642698-Virion
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pubmed:year |
1989
|
pubmed:articleTitle |
Characterization of HTLV-I in a T-cell line established from a patient with myelopathy.
|
pubmed:affiliation |
First Department of Internal Medicine, Nagasaki, University School of Medicine, Japan.
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|