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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1989-2-9
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pubmed:abstractText |
Based on 54 demented patients consecutively autopsied at the University of Pittsburgh, we studied the accuracy of clinicians in predicting the pathologic diagnosis. Thirty-nine patients (72.2%) had Alzheimer's disease, while 15 (27.7%) had other CNS diseases (four multi-infarct dementia; three Creutzfeldt-Jakob disease; two thalamic and subcortical gliosis; three Parkinson's disease; one progressive supranuclear palsy; one Huntington's disease; and one unclassified). Two neurologists independently reviewed the clinical records of each patient without knowledge of the patient's identity or clinical or pathologic diagnoses; each clinician reached a clinical diagnosis based on criteria derived from those of the NINCDS/ADRDA. In 34 (63%) cases both clinicians were correct, in nine (17%) one was correct, and in 11 (20%) neither was correct. These results show that in patients with a clinical diagnosis of dementia, the etiology cannot be accurately predicted during life.
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pubmed:grant | |
pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0028-3878
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
76-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2642615-Adult,
pubmed-meshheading:2642615-Aged,
pubmed-meshheading:2642615-Aged, 80 and over,
pubmed-meshheading:2642615-Alzheimer Disease,
pubmed-meshheading:2642615-Brain,
pubmed-meshheading:2642615-Creutzfeldt-Jakob Syndrome,
pubmed-meshheading:2642615-Dementia,
pubmed-meshheading:2642615-Dementia, Multi-Infarct,
pubmed-meshheading:2642615-Diagnostic Errors,
pubmed-meshheading:2642615-Female,
pubmed-meshheading:2642615-Humans,
pubmed-meshheading:2642615-Male,
pubmed-meshheading:2642615-Middle Aged,
pubmed-meshheading:2642615-Nerve Degeneration,
pubmed-meshheading:2642615-Nervous System Diseases,
pubmed-meshheading:2642615-Parkinson Disease
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pubmed:year |
1989
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pubmed:articleTitle |
Diagnosis of dementia: clinicopathologic correlations.
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pubmed:affiliation |
Department of Neurology, Veterans Administration Medical Center, Pittsburgh, PA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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