Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5-6
|
| pubmed:dateCreated |
1990-10-16
|
| pubmed:abstractText |
An NMR spectroscopy localization method that employs an inhomogeneous surface-spoiling magnetic field gradient has been applied to detect the 13C-[1H] signals from deep-lying liver tissue of rat in vivo. The method requires small gradient driving currents (less than 1 amp) and short gradient periods (approximately 0.5-1.6 ms). Thus, it is not likely to suffer from induced eddy currents and can detect short T2 resonances. We demonstrate that by employing a pulsed surface-spoiling gradient one can eliminate "contaminating" signals from the surface-lying tissues (muscle, fat and skin) while still maintaining the resonance linewidth resolution for the deep-lying tissue of interest (liver). The feasibility of using this localization approach to trace glucose conversion into glycogen is shown.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0952-3480
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
2
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
267-73
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading | |
| pubmed:year |
1989
|
| pubmed:articleTitle |
Localized 13C-[1H] NMR of rat liver in vivo using surface-spoiling gradients.
|
| pubmed:affiliation |
Department of Chemistry, Washington University, St. Louis, Missouri 63130-4899.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
|