Linked Life Data

2640978

Source:http://linkedlifedata.com/resource/pubmed/id/2640978

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1990-9-20
pubmed:abstractText
The cocaine epidemic of the past decade is undermining the efficacy of methadone maintenance (MM) treatment. In an open clinical trial, 12 MM patients addicted to cocaine were offered carbamazepine (CBZ) as a pharmacological adjunct in the treatment of cocaine dependence. Patients reported mild opiate withdrawal symptoms after initiation of CBZ treatment. Methadone serum trough (MST) levels taken before CBZ were compared with levels taken 7-10 days later, with an average decrease in MST levels of 60%. Patients (6) who continued on CBZ (average 144 days) reported a reduction in cocaine use, documented by random urine drug screens. Non-completers (6) who did not continue on CBZ (average 17 days) had no change in cocaine use.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1046-9516
pubmed:author
pubmed:issnType
Print
pubmed:volume
95
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
316-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Carbamazepine treatment of cocaine dependence in methadone maintenance patients with dual opiate-cocaine addiction.
pubmed:affiliation
University of Minnesota, Minneapolis 55455.
pubmed:publicationType
Journal Article