Linked Life Data

2625364

Source:http://linkedlifedata.com/resource/pubmed/id/2625364

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1990-4-2
pubmed:abstractText
The immunogenicity of a native whey protein-casein mixture (relation 60:40) was compared with an analogous mixture which had been subjected to Warren's hydrolysis procedure for splitting off sialic acid. The immunization was performed in 3 rabbits each, with a mean body weight of 4,200 g. After parenteral administration of an antigen dose corresponding to 2 mg protein for 6 times, 10 ml blood were withdrawn from each of the animals on day 80 of the immunization procedure. The serum of those rabbits which had been injected the native whey protein-casein mixture was shown to precipitate this antigen intensively as could be demonstrated by Mancini's test. The cross reaction with the sialic acid-free protein mixture was strongly diminished. Immunization with sialic acid-free whey protein-casein failed to produce worth-while antibody formation against this antigen. Only a moderate cross reaction with native whey protein-casein was detectable. These results may have potential consequences for the production of infant formulas and dietaries.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1011-6966
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
264-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Decreasing the immunogenicity of milk proteins by desialinization].
pubmed:affiliation
Baylor College of Medicine, Houston, Texas.
pubmed:publicationType
Journal Article, English Abstract