Linked Life Data

2625279

Source:http://linkedlifedata.com/resource/pubmed/id/2625279

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1990-4-2
pubmed:abstractText
Forty-three anterior lens capsules and epithelium from cataract patients extracted during extracapsular cataract surgery were examined by light microscopy and morphometry. An additional 15 lens capsules were examined by transmission electron microscopy. Morphometric examination revealed a positive correlation between age and the lens capsule thickness of 0.08 micron/year. The medium lens-capsule thickness of a 65-year-old human being was 8.65 microns. Light microscopy of cataractous anterior lens capsule and epithelium demonstrated proliferative changes with a multilamellar arrangement of the lens epithelial cells and an increase in the pleomorphic appearance of the cell and nucleus. Examination of the lens capsule revealed intracapsular foamy and vacuolic deposits with a localized splitting of the lens capsule. Transmission electromicroscopy established certain aspects of the lens capsule and epithelium. We found intracytoplasmatic single cilia and fibrillar intracytoplasmatic structures, with a diameter of 12-20 nm arranged in a pseudocrystalline fashion. The anterior lens capsule demonstrated similarly localized deviations from the normal homogeneous structure of type IV collagen, resulting in intracapsular deposition of fibrillar material. These observations suggest that cataractogenesis is associated with ultrastructural metaplastic and degenerative alteration of the lens epithelium and capsule.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0723-8045
pubmed:author
pubmed:issnType
Print
pubmed:volume
86
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
556-60
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Light and electron microscopy of the human, anterior cataract capsule].
pubmed:publicationType
Journal Article, English Abstract