Linked Life Data

2623055

Source:http://linkedlifedata.com/resource/pubmed/id/2623055

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1990-3-26
pubmed:abstractText
The effect of a scopolamine injection (1 mg/kg, IP) on response-to-change behavior was investigated in two experiments. After exploration of a T-maze with one arm black and the other white (Trial 1), rats were tested with both arms either black or white (Trial 2). Experiment 1 revealed that the opportunity to make body turns into the arms did not help scopolamine-injected rats to locate the changed arm after visual exploration of the arms during Trial 1. Saline-injected animals chose the changed arm. In Experiment 2, rats were allowed to move freely into the arms during Trial 1. During Trial 2, they were tested either from the same start as that used during Trial 1 or from a different start 180 degrees from the original start. While scopolamine-injected animals reacted appropriately to the change when tested from the same start, they were impaired when tested from the opposite start. In both conditions, saline-injected animals chose the changed arm. These results, together with others, support the notion that the cholinergic system plays a crucial role in the processing of distal information.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0031-9384
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
355-9
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Scopolamine impairs response-to-change based on distal cues in the rat.
pubmed:affiliation
C.N.R.S., Marseille, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't