Linked Life Data

2622921

Source:http://linkedlifedata.com/resource/pubmed/id/2622921

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1990-3-19
pubmed:abstractText
The complete cDNA sequence of G-6-PD is now known, and the application of modern technology has made it possible to rapidly accumulate sequence data regarding G-6-PD variants. The information that has become available demonstrates that there are several different types of G-6-PD A(-) but all have in common the mutation that is characteristic of G-6-PD A(+), viz. a substitution of G for A at nucleotide 376. Moreover, the same nucleotide substitutions have been found in Spanish and Italian subjects, indicating that the G-6-PD A(-) mutation is much more common in non-African populations than had been thought. G-6-PD Mediterranean, on the other hand, seems to be more uniform than had been thought previously. A wealth of information regarding structure/function relationship of enzymes is potentially available through the study of G-6-PD variants.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0361-7742
pubmed:author
pubmed:issnType
Print
pubmed:volume
319
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
39-50; discussion 51-4
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
The molecular biology of variation in glucose-6-phosphate dehydrogenase.
pubmed:affiliation
Research Institute of Scripps Clinic, La Jolla, CA 92037.
pubmed:publicationType
Journal Article