Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1990-3-20
pubmed:abstractText
Progesterone secretion by the corpora lutea (CL) of rats and rabbits declines from a peak, at about Day 16 of gestation, to near term (Day 22 rats and 28 rabbits). However there are major differences between the two species in CL growth and blood flow over this period. In the present work quantitative histological measurements were made of CL at these stages to examine the accompanying structural changes. Eight rats and five rabbits were examined at each stage: standard morphometric techniques were used. There was gross discrepancy between the two species in the histology of their CL at peak secretory activity. Although the proportions of the major tissue components were similar, the rabbit luteal cell (52 pl) was five times larger than that in the rat (9 pl). There was substantially less vascular and interstitial space in the rabbit, all characteristics which might affect transport processes between luteal cell cytoplasm and blood. Over the period examined, there was no change in CL volume in the rat but a 37% reduction in the rabbit due to loss of luteal cells. The vascular space in the rat, however, was reduced, whereas that in the rabbit declined only in proportion to the overall decrease in CL volume. These results show that structurally there is a substantial difference in patterns of early regression between the two species which reflect different mechanisms involved.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/2621138-1255563, http://linkedlifedata.com/resource/pubmed/commentcorrection/2621138-3401542, http://linkedlifedata.com/resource/pubmed/commentcorrection/2621138-3969930, http://linkedlifedata.com/resource/pubmed/commentcorrection/2621138-426308, http://linkedlifedata.com/resource/pubmed/commentcorrection/2621138-4734400, http://linkedlifedata.com/resource/pubmed/commentcorrection/2621138-5537770, http://linkedlifedata.com/resource/pubmed/commentcorrection/2621138-5688716, http://linkedlifedata.com/resource/pubmed/commentcorrection/2621138-6378858, http://linkedlifedata.com/resource/pubmed/commentcorrection/2621138-6486480, http://linkedlifedata.com/resource/pubmed/commentcorrection/2621138-6637856, http://linkedlifedata.com/resource/pubmed/commentcorrection/2621138-667257, http://linkedlifedata.com/resource/pubmed/commentcorrection/2621138-6747954, http://linkedlifedata.com/resource/pubmed/commentcorrection/2621138-7205787
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0021-8782
pubmed:author
pubmed:issnType
Print
pubmed:volume
166
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
191-201
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Quantitative comparison of luteal histology in the rat and rabbit: changes from mid- to late gestation.
pubmed:affiliation
Department of Anatomy and Human Biology, University of Western Australia, Nedlands.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't