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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1990-3-23
|
| pubmed:abstractText |
Investigators have suggested using relatives of cases as the control group when studying complex diseases thought to have a major genetic component. However, there is a concern about possible bias and we developed a model to examine the possibility of bias in the selection of relatives as the control group. Assuming the exposure-specific risks of disease remain constant over time, the results indicate that even when there is a correlation in the exposure status among relatives, selection of controls from relatives of cases does not, of itself, introduce bias in the estimate of effect.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0300-5771
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
18
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
985-9
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2621037-Bias (Epidemiology),
pubmed-meshheading:2621037-Case-Control Studies,
pubmed-meshheading:2621037-Environmental Exposure,
pubmed-meshheading:2621037-Humans,
pubmed-meshheading:2621037-Models, Genetic,
pubmed-meshheading:2621037-Odds Ratio,
pubmed-meshheading:2621037-Selection Bias,
pubmed-meshheading:2621037-Sibling Relations
|
| pubmed:year |
1989
|
| pubmed:articleTitle |
Selection bias in case-control studies using relatives as the controls.
|
| pubmed:affiliation |
Division of Epidemiology, UCLA School of Public Health 90024.
|
| pubmed:publicationType |
Journal Article
|