Linked Life Data

2620708

Source:http://linkedlifedata.com/resource/pubmed/id/2620708

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1990-3-22
pubmed:abstractText
The presence of bombesin-like material in nerves and endocrine cells of the gastrointestinal canal, the circulatory system and the lung of the caiman, Caiman crocodylus crocodylus, has been investigated with immunohistochemistry (IHC) and radioimmunoassay (RIA). The effect of bombesin has been studied on the vascularly perfused lung and on isolated strip preparations of the gut wall of the caiman, and on the circulatory system in vivo in both the caiman and the crocodile, Crocodylus porosus. Bombesin-like immunoreactivity is present in water and acid extracts of the muscle layer and the mucosal layer of the gut. IHC demonstrated a dense network of nerve fibres in the sub-mucosa, circular muscle layer and myenteric plexus of the whole gut. A more sparse innervation by single fibres often following septal edges or small vessels is found in the lung. Systemic vessels are innervated by a loose plexus of small fibre bundles. The levels of immunoreactive material in the lung and heart were low. Bombesin is excitatory on strip preparations of the smooth muscle layers of the intestinal wall, and causes an increase in inflow resistance in the perfused lung. In vivo, bombesin increases the blood flow in the left aorta and the coeliac artery.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0176-8638
pubmed:author
pubmed:issnType
Print
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
261-71
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Bombesin-like immunoreactivity and the effect of bombesin in the gut, circulatory system and lung of the caiman, Caiman crocodylus crocodylus, and the crocodile, Crocodylus porosus.
pubmed:affiliation
Department of Zoophysiology, University of Göteborg, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't