Linked Life Data

2620272

Source:http://linkedlifedata.com/resource/pubmed/id/2620272

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1990-3-23
pubmed:abstractText
Cytogenetic studies using Giemsa R-bands after a short term culture of bone marrow or peripheral blood were done in 20 cases of acute promyelocytic leukemia (APL), including three cases of microgranular variant. As a result, t (15;17) cells were found in all the cells, and the percentages of the abnormal cells were 38-100%. In 2 cases, t(15;17) was seen in 88% and 65% of the cells in cultured specimens, whereas no such translocation was seen in direct specimens. Among 6 cases treated with tretinoin, 5 achieved complete remission, and among 14 cases treated by HOAP protocol 2 achieved complete remission. Reexamination of 4 of these cases during the stage of complete remission failed to find t(15;17). These data revealed that t(15;17) may probably be present in all cases of APL, and therefore is a very useful diagnostic criterion, especially in cases of micro granular APL. But the detection rate is determined by methodology, which requires special precaution.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0376-2491
pubmed:author
pubmed:issnType
Print
pubmed:volume
69
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
434-7, 30
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Acute promyelocytic leukemia and 15;17 chromosome translocation].
pubmed:publicationType
Journal Article, English Abstract