Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
|
pubmed:dateCreated |
1990-3-21
|
pubmed:abstractText |
Various prognostic factors were studied in 29 patients with stage III or IV ovarian cancer who responded to initial chemotherapy after initial diagnostic surgery. The half-life of CA 125 in serum during initial chemotherapy was the most important prognostic indicator for survival (P less than 0.001) and the chance of achieving complete remission (P = 0.012). A CA 125 half-life of less than 20 days, 20-40 days and greater than 40 days appears to identify patients with a good, intermediate or poor prognosis, the two year actuarial survival being 76%, 48% and 0% respectively. The change of achieving a complete remission was 15% and 67% respectively for patients with a serum CA 125 half-life of greater than 20 or less than 20 days.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0306-5456
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
96
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1395-9
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:2620051-Antigens, Tumor-Associated, Carbohydrate,
pubmed-meshheading:2620051-Female,
pubmed-meshheading:2620051-Half-Life,
pubmed-meshheading:2620051-Humans,
pubmed-meshheading:2620051-Ovarian Neoplasms,
pubmed-meshheading:2620051-Prognosis,
pubmed-meshheading:2620051-Proportional Hazards Models,
pubmed-meshheading:2620051-Survival Rate
|
pubmed:year |
1989
|
pubmed:articleTitle |
The prognostic significance of the half-life of serum CA 125 in patients responding to chemotherapy for epithelial ovarian carcinoma.
|
pubmed:affiliation |
Department of Medicine, Royal Marsden Hospital, London.
|
pubmed:publicationType |
Journal Article
|