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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1990-2-27
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pubmed:abstractText |
11 beta,18-Epoxy-2 alpha,3 alpha,18,21-tetrahydroxy-5 alpha,17 alpha- pregnan-20-one (2 alpha-hydroxy-3 alpha,5 alpha-tetrahydro-17-isoaldosterone) and its apo isomer have been identified by high-field NMR studies, supported by thermospray HPLC/MS, to be among the major polar metabolites formed from incubation of aldosterone with rat liver microsomal fraction. Indications that unreduced 2 alpha-hydroxy-aldosterone is also present among the metabolites have still to be confirmed.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0022-4731
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
33
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1119-25
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2615356-Aldosterone,
pubmed-meshheading:2615356-Animals,
pubmed-meshheading:2615356-Chromatography, High Pressure Liquid,
pubmed-meshheading:2615356-Magnetic Resonance Spectroscopy,
pubmed-meshheading:2615356-Male,
pubmed-meshheading:2615356-Mass Spectrometry,
pubmed-meshheading:2615356-Microsomes, Liver,
pubmed-meshheading:2615356-Pregnanes,
pubmed-meshheading:2615356-Rats,
pubmed-meshheading:2615356-Rats, Inbred Strains
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pubmed:year |
1989
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pubmed:articleTitle |
18-substituted steroids--Part 17. 2 alpha-hydroxylated liver metabolites of aldosterone identified by high-field [1H]NMR spectroscopy.
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pubmed:affiliation |
Department of Laboratory Medicine, Miriam Hospital, Providence, Rhode Island.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|