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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1990-3-13
|
| pubmed:abstractText |
Gastric antral endoscopic pinch biopsies from a group of dyspeptic patients were analysed for acute and chronic inflammatory cell numbers in the lamina propria and surface epithelial layer using computer-linked graphic tablet planimetry, and independently graded for Campylobacter pylori (CP) infection using a visual scoring system with grade 1 assessed as patchy epithelial infection and grade 2 as a continuous layer of organisms on the mucosal surface extending into gastric pits. The study group consisted of 36 patients (18 duodenitis; 18 non-ulcer dyspepsia). Within the 140 biopsies analysed, grade 1 and 2 biopsies had significantly higher acute and chronic inflammatory cell counts than CP-negative biopsies (grade 0) in lamina and surface epithelium (P less than 0.001). Acute inflammatory cell counts were significantly higher in the surface epithelium in grade 1 (P less than 0.05) and grade 2 biopsies (P less than 0.001) but chronic inflammatory cells were only higher in grade 1 (P less than 0.01). No significant differences were present between grade 1 and grade 2 biopsies for any parameter. This study confirms that highly significant quantitative differences in the inflammatory status are related to the presence of CP.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0022-3417
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
159
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
281-5
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2614572-Acute Disease,
pubmed-meshheading:2614572-Adolescent,
pubmed-meshheading:2614572-Adult,
pubmed-meshheading:2614572-Aged,
pubmed-meshheading:2614572-Biopsy,
pubmed-meshheading:2614572-Campylobacter,
pubmed-meshheading:2614572-Chronic Disease,
pubmed-meshheading:2614572-Female,
pubmed-meshheading:2614572-Gastritis,
pubmed-meshheading:2614572-Gastroscopy,
pubmed-meshheading:2614572-Humans,
pubmed-meshheading:2614572-Male,
pubmed-meshheading:2614572-Microcomputers,
pubmed-meshheading:2614572-Middle Aged,
pubmed-meshheading:2614572-Pyloric Antrum
|
| pubmed:year |
1989
|
| pubmed:articleTitle |
Investigation of the relationship between gastric antral inflammation and Campylobacter pylori using graphic tablet planimetry.
|
| pubmed:affiliation |
Department of Medicine, Queen's University, Belfast, Northern Ireland.
|
| pubmed:publicationType |
Journal Article
|