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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1990-3-15
pubmed:abstractText
One hundred twenty-lead body surface potential maps (BSPMs) were recorded immediately before and 24 hours after coronary angioplasty (PTCA) in 24 patients with symptomatic coronary artery disease (single-vessel in 21 and two-vessel in 3). All PTCAs were uncomplicated and successful. The modified Gensini score decreased in every patient and the mean score fell from 43 +/- 36 to 21 +/- 28 (p less than 0.001). Resting spatial patterns of QRS, ST-segment, and T wave integral distributions over the torso surface were unchanged from before to after PTCA. Quantitative temporal subtraction maps, however, revealed a large precordial area of decreased T wave integral values after PTCA. The sum (sigma) positive T wave integrals fell from 20,501 +/- 10,544 microV.s before PTCA to 17,647 +/- 10,310 microV.s after PTCA (p less than 0.02). In contrast, the sigma positive QRS (10,115 +/- 4,848 microV.s before PTCA vs. 9,656 +/- 4,556 microV.s after PTCA) and the sigma negative ST integrals (-2,489 +/- 1,467 microV.s before PTCA vs. -2,359 +/- 1,505 microV.s after PTCA) were unchanged (NS). Thus, successful PTCA does not produce any persistent change in depolarization or early repolarization electrocardiographic variables but is associated with a decrease in late repolarization potentials that persists for at least 24 hours after the procedure. The pathophysiology of this persistent change is speculative, but myocardial ischemia during the PTCA procedure is a likely possibility. The clinical significance, including predictive value for subsequent stenosis, and the natural history of T wave effect remain incompletely defined. These data suggest that measures to decrease myocardial ischemia during PTCA are warranted.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0022-0736
pubmed:author
pubmed:issnType
Print
pubmed:volume
22 Suppl
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
91-8
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Persistent changes in the body surface electrocardiogram following successful coronary angioplasty.
pubmed:affiliation
Department of Medicine, University of Alberta, Edmonton, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't