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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
1990-3-9
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pubmed:abstractText |
Factor VII and prekallikrein activities were studied in 37 patients with liver cirrhosis who were in a decompensated state. Sixteen of them died 30-70 days after admission; 21 survived and were discharged after 30-80 days. Seven who died and six survivors had signs of hyperfibrinolysis: factor VII activity differentiated the two groups independently of the presence of hyperfibrinolysis. The presence of hyperfibrinolysis significantly reduced prekallikrein activity, which did not differentiate clearly survivors from non-survivors. Long term follow up of survivors showed a good correlation between factor VII and prekallikrein activities with long term survival. Hyperfibrinolysis seemed to influence the clinical course of patients: 87% of patients with hyperfibrinolysis who died had fatal haemorrhagic episodes. Low factor VII activity may be a precursor of terminal liver insufficiency.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2613916-1002840,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2613916-1201157,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2613916-13434757,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2613916-3009109,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2613916-3635353,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2613916-3639088,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2613916-4082093,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2613916-6141134,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2613916-6418623,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2613916-64749,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2613916-6534818,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2613916-6564063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2613916-6779978
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0021-9746
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1246-9
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2613916-Adult,
pubmed-meshheading:2613916-Aged,
pubmed-meshheading:2613916-Aged, 80 and over,
pubmed-meshheading:2613916-Bilirubin,
pubmed-meshheading:2613916-Blood Coagulation Disorders,
pubmed-meshheading:2613916-Factor VII,
pubmed-meshheading:2613916-Female,
pubmed-meshheading:2613916-Fibrinolysis,
pubmed-meshheading:2613916-Humans,
pubmed-meshheading:2613916-Liver Cirrhosis,
pubmed-meshheading:2613916-Male,
pubmed-meshheading:2613916-Middle Aged,
pubmed-meshheading:2613916-Prekallikrein,
pubmed-meshheading:2613916-Prognosis
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pubmed:year |
1989
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pubmed:articleTitle |
Interrelation between factor VII, prekallikrein, and hyperfibrinolysis in advanced cirrhosis.
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pubmed:affiliation |
Istituto di I Clinica Medica, University La Sapienza, Rome, Italy.
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pubmed:publicationType |
Journal Article
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