Linked Life Data

2610955

Source:http://linkedlifedata.com/resource/pubmed/id/2610955

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1990-3-1
pubmed:abstractText
(1S,2S,3R,4R,5R,8S,10R,12S)-4-Hydroxy-2,3:15,16-diepoxycleroda-13( 16),14- dieno-17,12:18,1-biscarbolactone, C20H22O7, Mr = 374, m.p. = 509-511 K, orthorhombic, P2(1)2(1)2(1), a = 9.191 (2), b = 13.8230 (6), c = 26.956 (2) A, V = 3424.50 A3, Z = 8, Dx = 1.450, Dm (by flotation) = 1.446 g cm-3, lambda (Cu K alpha) = 1.5418 A, mu = 8.20 cm-1, F(000) = 1584, T = 295 K, R = 0.0464, wR = 0.0579 for 3437 observed reflections. The asymmetric unit contains two molecules. The structure resembles that of a similar compound [Swaminathan, Sinha, Bhatt & Sabata (1988). Acta Cryst. C44, 1421-1424] with atom H(15) replacing the tertiary hydroxyl group at C(8). Atoms H(4) and H(15) are alpha- and beta-oriented respectively at sites C(12) and C(8). The terpene ring A is locked into a boat conformation by the C(1)-C(4) lactone bridge. The hydroxyl at C(4) is involved in hydrogen bonding.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0108-2701
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
45 ( Pt 1)
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
134-6
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Structure of tinosporide, a diterpenoid furanolactone from Tinospora cordifolia Miers.
pubmed:affiliation
Physics Department, Indian Institute of Technology, Powai, Bombay.
pubmed:publicationType
Journal Article