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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1990-2-28
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pubmed:abstractText |
The interaction of leptospires with polymorphonuclear neutrophils (PMN) was examined by the luminol-dependent chemiluminescence (CL) test. Whole blood CL changed in relation to the stage of leptospiral infection both in susceptible (SUS) and resistant (RES) rats. The intensity of CL grew with an increasing number of leptospires in the blood. CL responses were observed in isolated PMN upon exposure to living leptospires. In contrast, the same bacteria, having been inactivated by formalin, did not stimulate PMN. A variation was found in the CL response by different living strains of Leptospira. The CL intensity was arranged as follows: L. illini greater than L. biflexa greater than L. interrogans avirulent strains greater than L. interrogans virulent strains. The CL response was markedly enhanced by an opsonization of leptospires. Specific opsonization was shown to increase the rate of phagocytosis of leptospires with relation to the CL response.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0934-8840
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
272
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
36-46
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:2610812-Animals,
pubmed-meshheading:2610812-Leptospira,
pubmed-meshheading:2610812-Leptospira interrogans,
pubmed-meshheading:2610812-Luminescent Measurements,
pubmed-meshheading:2610812-Male,
pubmed-meshheading:2610812-Neutrophils,
pubmed-meshheading:2610812-Opsonin Proteins,
pubmed-meshheading:2610812-Phagocytosis,
pubmed-meshheading:2610812-Rats,
pubmed-meshheading:2610812-Virulence
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pubmed:year |
1989
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pubmed:articleTitle |
Chemiluminescence and phagocytic responses of rat polymorphonuclear neutrophils to leptospires.
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pubmed:affiliation |
Department of Preventive Dentistry, School of Dentistry, Ishikari-Tobetsu, Japan.
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pubmed:publicationType |
Journal Article
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