rdf:type |
|
lifeskim:mentions |
umls-concept:C0021759,
umls-concept:C0026809,
umls-concept:C0087111,
umls-concept:C0100748,
umls-concept:C0442805,
umls-concept:C1257771,
umls-concept:C1257772,
umls-concept:C1334131,
umls-concept:C1515655,
umls-concept:C1516960,
umls-concept:C1709634
|
pubmed:issue |
3
|
pubmed:dateCreated |
1990-2-13
|
pubmed:abstractText |
The in vivo effect of human EDF on erythroid precursors (CFU-E and BFU-E) was investigated in normal and bled mice. In anemic (bled) mice, EDF treatment led to significant dose-dependent rises in the CFU-E and BFU-E levels of bone marrow. An elevation in the level of CFU-E was also seen in the spleen. In normal mice, a significant elevation in the level of bone marrow BFU-E was observed. Thus, EDF has an effect on erythropoiesis in anemic and normal mice in vivo.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0006-291X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
29
|
pubmed:volume |
165
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1155-61
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:2610684-Activins,
pubmed-meshheading:2610684-Anemia,
pubmed-meshheading:2610684-Animals,
pubmed-meshheading:2610684-Bone Marrow Cells,
pubmed-meshheading:2610684-Cell Differentiation,
pubmed-meshheading:2610684-Colony-Forming Units Assay,
pubmed-meshheading:2610684-Dose-Response Relationship, Drug,
pubmed-meshheading:2610684-Erythroid Precursor Cells,
pubmed-meshheading:2610684-Erythropoiesis,
pubmed-meshheading:2610684-Humans,
pubmed-meshheading:2610684-Inhibins,
pubmed-meshheading:2610684-Kinetics,
pubmed-meshheading:2610684-Male,
pubmed-meshheading:2610684-Mice,
pubmed-meshheading:2610684-Mice, Inbred C3H,
pubmed-meshheading:2610684-Recombinant Proteins,
pubmed-meshheading:2610684-Spleen
|
pubmed:year |
1989
|
pubmed:articleTitle |
In vivo treatment with erythroid differentiation factor (EDF/activin A) increases erythroid precursors (CFU-E and BFU-E) in mice.
|
pubmed:affiliation |
Central Research Laboratories, Ajinomoto Co., Inc., Kawasaki, Japan.
|
pubmed:publicationType |
Journal Article
|