2608581

Source:http://linkedlifedata.com/resource/pubmed/id/2608581

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0003962, umls-concept:C0020541, umls-concept:C0221013
pubmed:issue	764
pubmed:dateCreated	1990-2-12
pubmed:abstractText	We report a case of systemic mastocytosis (SM) presenting as ascites and portal hypertension. The haematological picture at presentation was suggestive of chronic myelomonocytic leukaemia. Initial difficulties in making a diagnosis of SM were encountered as the cutaneous signs were atypical. The correct diagnosis was established only after tissue sections were appropriately stained for mast cells. The liver biopsy showed portal and sinusoidal mast cell infiltration, portal fibrosis and evidence of hepatic venous outflow obstruction. The disease progressed rapidly and recurrent massive ascites was a dominant problem. This case illustrates again the problems of making a diagnosis of SM especially when the clinical picture is atypical. Ascites as a presenting manifestation of SM has been reported previously in only six patients. Published cases of SM with portal hypertension or ascites or both are reviewed.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/2608581-1059474, http://linkedlifedata.com/resource/pubmed/commentcorrection/2608581-114472, http://linkedlifedata.com/resource/pubmed/commentcorrection/2608581-2579553, http://linkedlifedata.com/resource/pubmed/commentcorrection/2608581-265679, http://linkedlifedata.com/resource/pubmed/commentcorrection/2608581-3706370, http://linkedlifedata.com/resource/pubmed/commentcorrection/2608581-3838239, http://linkedlifedata.com/resource/pubmed/commentcorrection/2608581-3860469, http://linkedlifedata.com/resource/pubmed/commentcorrection/2608581-6174198, http://linkedlifedata.com/resource/pubmed/commentcorrection/2608581-631492, http://linkedlifedata.com/resource/pubmed/commentcorrection/2608581-6965282, http://linkedlifedata.com/resource/pubmed/commentcorrection/2608581-7085913
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0234135
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	0032-5473
pubmed:author	pubmed-author:AzzawiSS, pubmed-author:Liu YinJ AJA, pubmed-author:NarayananM NMN, pubmed-author:TurckW PWP, pubmed-author:WarnesT WTW
pubmed:issnType	Print
pubmed:volume	65
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	394-6
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:2608581-Ascites, pubmed-meshheading:2608581-Humans, pubmed-meshheading:2608581-Hypertension, Portal, pubmed-meshheading:2608581-Male, pubmed-meshheading:2608581-Mastocytosis, pubmed-meshheading:2608581-Middle Aged
pubmed:year	1989
pubmed:articleTitle	Portal hypertension and ascites in systemic mastocytosis.
pubmed:affiliation	Department of Clinical Haematology, Royal Infirmary, Manchester, UK.
pubmed:publicationType	Journal Article, Case Reports