Linked Life Data

2607464

Source:http://linkedlifedata.com/resource/pubmed/id/2607464

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1990-2-22
pubmed:abstractText
1. The effects of plasmapheresis on the responses of rapidly adapting receptors (RARs) and slowly adapting receptors (SARs) of the airways to pulmonary venous congestion were examined in dogs anaesthetized with alpha-chloralose. Pulmonary venous congestion was produced in a graded manner by partial obstruction of the mitral valve sufficient to raise the mean left atrial pressure by 5, 10 and 15 mmHg. Plasmapheresis was performed by withdrawing 10% of blood volume twice. 2. Both RARs (n = 11) and SARs (n = 5) responded to pulmonary venous congestion by increasing their activities. The responses of the former were proportionately greater. 3. After plasmapheresis which reduced the concentration of plasma proteins by 12.3 +/- 1.0%, the responses of the RARs to pulmonary venous congestion were enhanced significantly. There was no significant change in the responses of SARs. 4. In another set of six RARs, the effects of graded pulmonary venous congestion were investigated twice with an interval of 45 min between the two observations. No significant differences were noted between the two responses. 5. Collection of lymph from the tracheobronchial lymph duct (n = 6) showed that after plasmapheresis, there was an increase in the control lymph flow. In addition, the lymph flow was enhanced during pulmonary venous congestion (mean left atrial pressure increased by 10 mmHg). 6. It is suggested that a natural stimulus for the excitation of the RAR is a function of the fluid fluxes in the pulmonary extravascular space.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-101311, http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-13663218, http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-13779014, http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-2778723, http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-3236242, http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-3416233, http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-3443966, http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-3698217, http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-3948344, http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-4568412, http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-4601625, http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-4713847, http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-5387024, http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-6017888, http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-6803268, http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-6833047, http://linkedlifedata.com/resource/pubmed/commentcorrection/2607464-7296783
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0022-3751
pubmed:author
pubmed:issnType
Print
pubmed:volume
416
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
79-91
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Plasmapheresis affects responses of slowly and rapidly adapting airway receptors to pulmonary venous congestion in dogs.
pubmed:affiliation
Division of Cardiology, University of Alberta, Edmonton, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't