Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1990-2-15
pubmed:abstractText
Salivary nitrate concentration has often been used as a measure of human intake of nitrate. However, our findings indicate that this is not a reliable indicator because the nitrate concentration varies with salivary flow-rate and thus depends on the sampling procedure. Parotid or whole saliva was collected from up to six volunteers under carefully controlled conditions. The effects of stimulating saliva production by chewing on silicon tube (mechanical stimulation) or by sucking citric acid from cotton wool (gustatory stimulation) were investigated. Chewing decreased the average nitrate (plus nitrite) concentration in whole saliva by 59% and the nitrate concentration in parotid saliva (which does not contain nitrite) by 53%, relative to unstimulated saliva. Citric acid stimulation decreased the average parotid salivary nitrate concentration by 88%. Stimulation of salivary secretion increased the total salivary nitrate output and the extent of reduction of nitrate to nitrite for most subjects. The unstimulated parotid salivary nitrate concentration was, on average, 2.8 times the nitrate plus nitrite concentration in unstimulated whole saliva.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0278-6915
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
675-80
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Nitrate and nitrite concentrations in human saliva: variations with salivary flow-rate.
pubmed:affiliation
Norsk Hydro Research Centre, University of Oslo, Norway.
pubmed:publicationType
Journal Article